Publications of Grape polyphenol Group
Our last publications !
- Grapevine woody tissues accumulate stilbenoids following bud burst16 novembre 2023 - 20 novembre 2025In this collobarative work, we show that biologically active phenolic compounds, including stilbenoids,accumulate in the woody canes during bud burst.
- trans-Resveratrol as a Health Beneficial Molecule: Activity, Sources, and Methods of Analysis.10 septembre 2023 - 10 septembre 2025In this study we developed in vitro shoot cultures of grapevine cultivars from Poland as a source of polyphenols with cosmetics interest.
- Shoot cultures of Vitis vinifera (vine grape) different cultivars as a promising innovative cosmetic raw material the phytochemical profiling, antioxidant potential and whitening activity.10 septembre 2023 - 10 septembre 2025In this study we developed in vitro shoot cultures of grapevine cultivars from Poland as a source of polyphenols with cosmetics interest.
- Combined omics approaches expose metabolite-microbiota correlations in grape berries of three cultivars of Douro wine region10 juillet 2023 - 10 juillet 2025In this study, we hypothesized that the grapevine cultivar has a direct effect on the metabolome of grape berries, subsequently affecting their microbial fingerprint.
- Terroir Influence on Polyphenol Metabolism from Grape Canes: A Spatial Metabolomic Study at Parcel Scale10 juin 2023 - 10 juin 2025The aim of this study was to assess the terroir influence on the polyphenol composition ingrape canes using a spatial metabolomics approach.
- Benzothiadiazole Affects Grape Polyphenol Metabolism and Wine Quality in Two Greek Cultivars: Effects during Ripening Period over Two Years10 février 2023 - 10 février 2025A research performed in collaboration with Agricultural University of Athens on new pioneer practice to enrich polyphenols in grape by the application of biostimulants on grapevines
- Canopy management through crop forcing impacts grapevine cv. ‘Touriga Nacional’ performance, ripening and berry metabolomics profile9 janvier 2023 - 9 janvier 2025Read our collaborative article with Pr Queiroz from the University of Porto and Pr Geros from the University of Minho, (Portugal). Climate changes are speeding up the maturation of grapes, but warmer temperatures often uncouple technical and phenolic maturity. We tested the efficacy of crop forcing in delaying the maturation of cv. ‘Touriga Nacional’ vines of the Douro Region, and their impacts on plant performance, berry quality attributes and metabolome
- Cassia sieberiana root bark used in traditional medicine in Togo: Anthelmintic property against Haemonchus contortus and tannins composition14 décembre 2022 - 14 décembre 2025A collaborative article with the laboratory Synthese et Isolement de Molecules Bioactives (SIMBA), Tours.We validated the traditional application of C. sieberiana root bark as a dewormer. We determined the metabolic composition of the extracts by UPLC-MS/MS.
- Identifying Major Drivers of Antioxidant Activities in Complex Polyphenol Mixtures from Grape Canes23 juin 2022 - 23 juin 2025In this article published in Molecules, we identified the main drivers of antioxidant activities in polyphenol-rich grape cane extracts in European varieties. Congrats to our PhD student Manon Ferrier for this article!
- Abscisic Acid and Chitosan Modulate Polyphenol Metabolism and Berry Qualities in the Domestic White-Colored Cultivar Savvatiano ine cv. ‘Touriga Nacional’ performance, ripening and berry metabolomics profile22 juin 2022 - 22 juin 2025Read our collaborative article with Pr Kosteridis from University of Athens (Greece).Biostimulants have emerged as innovative technical solutions to synthetic chemicals, providing sustainable alternative for grapevine protection. We evaluated the impact on a polyphenol metabolism in a local Greek cultivar.
- Impact of Deficit Irrigation on Grapevine cv. ‘Touriga Nacional’ during Three Seasons in Douro Region: An Agronomical and Metabolomics Approach9 mars 2022Impact of Deficit Irrigation on Grapevine cv. ‘Touriga Nacional’ during Three Seasons in Douro Region: An Agronomical and Metabolomics Approach , a collaborative article with Pr Geros from the University do Minho, (Portugal)
- 2020. Billet K, Malinowska MA, Munsch T, Unlubayir M, Adler S, Delanoue G, Lanoue A. Semi-targeted Metabolomics to validate biomarkers of grape downy mildew infection under field conditions. Plants 9 (8) 1008. DOI:10.3390/plants9081008
- 2020. Malinowska MA, Billet K, Drouet S, Munsch T, Unlubayir M, Tungmunnithum D, Giglioli-Guivarc'h N, Hano C, Lanoue A. Grape cane extracts as multifunctional rejuvenating cosmetic ingredient: Evaluation of sirtuin activity, tyrosinase inhibition and bioavailability potential. Molecules 25(9):2203 DOI: 10.3390/molecules25092203
- 2020. Billet K, Malinowska MA, Munsch T, Unlubayir M, Dugé de Bernonville T, Besseau S, Courdavault V, Oudin A, Pichon O, Clastre M, Giglioli-Guivarc’h N, Lanoue A. Stilbenoid-enriched grape cane extracts for the biocontrol of grapevine diseases in "Biological Control" eds Mérillon JM, Ramawat KG. Springer Nature. DOI: 10.1007/978-3-030-51034-3_9
- 2020. Martins V, Billet K, Garcia A, Lanoue A, Gerós H. Exogenous calcium deflects grape berry metabolism towards the production of more stilbenoids and less anthocyanins. Food Chemistry 313:126123 DOI : 10.1016/j.foodchem.2019.126123
- 2019. Billet K, Delanoue G, Houillé B, Arnault I, Besseau S, Oudin A, Courdavault V, Marchand PA, Giglioli-Guivarc’h N, Guérin L, Lanoue A. Vineyard evaluation of stilbenoid-rich grape cane extracts against downy mildew: a large-scale study. Pest Management Science 75(5):1252-1257 DOI: 10.1002/ps.5237
- 2018. Billet K, Houillé B, Dugé de Bernonville T, Besseau S, Courdavault V, Oudin A, Delanoue G, Guerin L, Papon N, Clastre N, Giglioli-Guivarc'h N, Lanoue A. Field-based metabolomics of Vitis vinifera L. stems provides new insights for genotype discrimination and polyphenol metabolism structuring. Frontiers in Plant Science. DOI: 10.3389/fpls.2018.00798
- 2018. Billet K, Houillé B, Besseau S, Mélin C, Oudin A, Papon N, Courdavault V, Clastre M, Gilioli-Guivarc’h N, Lanoue A. Mechanical stress rapidly induces E-resveratrol and E-piceatannol biosynthesis in grape canes stored as freshly-pruned byproduct. Food Chemistry. 240:1022-1027. DOI: 10.1016/j.foodchem.2017.07.105
- 2015. Houillé B, Besseau S, Courdavault V, Oudin A, Delanoue G, Guerin L, Simkin AJ, papon N, Clastre N, Giglioli-Guivarc'h N, Lanoue A. Composition and tissue-specific distribution of stilbenoids in grape canes are affected by downy mildew pressure in the vineyard. Journal of Agricultural Food Chemistry. 63 (38):8472–8477. DOI: 10.1021/acs.jafc.5b02997
- 2015. Houillé B, besseau S, Courdavault V, Oudin A, Glévarec G, Delanoue G, Guerin L, Simkin AJ, Papon N, Claste M, Giglioli-Guivarc'h N, Lanoue A. Biosynthetic origin of E-resveratrol accumulation in grape canes during postharvest storage. Journal of Agricultural Food Chemistry 63 (5): 1631-1638. DOI: 10.1021/jf505316a
- 2014. Houillé B, Papon N, Boudesocque L, Besseau S, Courdavault V, Bourdeaud E, Enguehard-Gueiffier C, Giglioli-Guivarc'h N, Bouchara JP, Guilliard J, Lanoue A. Antifungal activity of resveratrol analog and oligomer molecules against Candida species. Journal of Natural Products 77(7):1658-1662. DOI: 10.1021/np5002576
