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Characterization of specialized plant metabolisms by developing biotechnological and metabolic engineering processes aimed at producing metabolites of interest for pharmaceutical, cosmetic or agronomic applications
Our mission
The Plant Biomolecules and Biotechnology (BBV) laboratory is developing several research projects on the characterization of specialized plant metabolisms by developing biotechnological and metabolic engineering processes aimed at producing metabolites of interest for pharmaceutical, cosmetic or agronomic applications.
These projects are based on molecular biology, cell biology, biochemistry and genomics and metabolomics approaches.
These projects are based on molecular biology, cell biology, biochemistry and genomics and metabolomics approaches.
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Our TEAM
Permanent Professors and associate Professors
Post-doc and PhD Students
Engineers and technical staff
Read our last articles
- Medicinal plants enter the single-cell multi-omics era5 août 2023 - 26 août 2025Our new spotlight published in Trends in Plant Science, on a report by Li et al on single-cell multi-omics approach used to elucidate the architecture and regulation of anticancer alkaloid biosynthesis in medicinal plants.
- The evolutionary pattern of cocaine and hyoscyamine biosynthesis provides strategies to produce tropane alkaloids30 mai 2023 - 21 février 2026In this highlight published in ChemBioChem, we discuss how tropane alkaloid biosynthesis evolved via the recruitment of two distinct and convergent pathways in Erythroxylaceae and Solanaceae.
- Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging21 février 2023 - 21 février 2025In this study published in Phytochemistry, we explore how matrix assisted laser desorption ionization (MALDI) and desorption electrospray ionization (DESI) mass spectrometry imaging (MSI) can be used in the investigation of a proposed biosynthetic pathway by localizing reserpine and the theoretical intermediates of it
- Convergent evolution for antibiotic biosynthesis in bacteria and animals21 février 2023 - 21 février 2025A spotlight in Trends in genetics about the convergent evolution for antibiotic biosynthesis in bacteria and animals.
- Benzothiadiazole Affects Grape Polyphenol Metabolism and Wine Quality in Two Greek Cultivars: Effects during Ripening Period over Two Years10 février 2023 - 10 février 2025A research performed in collaboration with Agricultural University of Athens on new pioneer practice to enrich polyphenols in grape by the application of biostimulants on grapevines
- Canopy management through crop forcing impacts grapevine cv. ‘Touriga Nacional’ performance, ripening and berry metabolomics profile9 janvier 2023 - 9 janvier 2025Read our collaborative article with Pr Queiroz from the University of Porto and Pr Geros from the University of Minho, (Portugal). Climate changes are speeding up the maturation of grapes, but warmer temperatures often uncouple technical and phenolic maturity. We tested the efficacy of crop forcing in delaying the maturation of cv. ‘Touriga Nacional’ vines of the Douro Region, and their impacts on plant performance, berry quality attributes and metabolome
- An updated version of the Madagascar periwinkle genome21 décembre 2022 - 21 décembre 2025This updated version should ease evolutionary studies leading to a better understanding of MIA biosynthetic pathway evolution.
- Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism15 décembre 2022 - 15 décembre 2025Read our new study with Pr Chao SUN’s group, on single-cell RNA sequencing of Catharanthus roseus leaf published in Nature plants!
- Cassia sieberiana root bark used in traditional medicine in Togo: Anthelmintic property against Haemonchus contortus and tannins composition14 décembre 2022 - 14 décembre 2025A collaborative article with the laboratory Synthese et Isolement de Molecules Bioactives (SIMBA), Tours.We validated the traditional application of C. sieberiana root bark as a dewormer. We determined the metabolic composition of the extracts by UPLC-MS/MS.
Read more articles from 2022 and 2021