Website Research Unit BBV
Characterization of specialized plant metabolisms by developing biotechnological and metabolic engineering processes aimed at producing metabolites of interest for pharmaceutical, cosmetic or agronomic applications
Financial Partners of BIOPROPHARM research project
Our mission
The Plant Biomolecules and Biotechnology (BBV) laboratory is developing several research projects on the characterization of specialized plant metabolisms by developing biotechnological and metabolic engineering processes aimed at producing metabolites of interest for pharmaceutical, cosmetic or agronomic applications.
These projects are based on molecular biology, cell biology, biochemistry and genomics and metabolomics approaches.
These projects are based on molecular biology, cell biology, biochemistry and genomics and metabolomics approaches.
Breaking news
- The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids in monoterpene indole alkaloid synthesis24 novembre 2023 - 1 janvier 2026Our results published in Communications Biology, a Portfolio Nature journal, pave the way towards alkaloid bioproduction in yeast, and among them, yohimbine, rauwolscine, corynathine (and their derivatives), therapetuic molecules with selective affinity for α2-adrenergic and α1-adrenergic receptors,
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Our TEAM
Permanent Professors and associate Professors
Post-doc and PhD Students
Engineers and technical staff
Read our last articles
- Grapevine woody tissues accumulate stilbenoids following bud burst16 novembre 2023 - 20 novembre 2025In this collobarative work, we show that biologically active phenolic compounds, including stilbenoids,accumulate in the woody canes during bud burst.
- Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast7 novembre 2023 - 26 août 2025Published in Nature Chemical Biology, this collaborative work demonstrates a scalable de novo manufacturing platform for bioactive monoterpenoid indole alkaloids (MIAs, plant metabolites that possess various medicinal properties) in yeast and provides a foundation for further pathway refactoring toward microbial biosynthesis of both native and new-to-nature MIAs.
- trans-Resveratrol as a Health Beneficial Molecule: Activity, Sources, and Methods of Analysis.10 septembre 2023 - 10 septembre 2025In this study we developed in vitro shoot cultures of grapevine cultivars from Poland as a source of polyphenols with cosmetics interest.
- Shoot cultures of Vitis vinifera (vine grape) different cultivars as a promising innovative cosmetic raw material the phytochemical profiling, antioxidant potential and whitening activity.10 septembre 2023 - 10 septembre 2025In this study we developed in vitro shoot cultures of grapevine cultivars from Poland as a source of polyphenols with cosmetics interest.
- Combined omics approaches expose metabolite-microbiota correlations in grape berries of three cultivars of Douro wine region10 juillet 2023 - 10 juillet 2025In this study, we hypothesized that the grapevine cultivar has a direct effect on the metabolome of grape berries, subsequently affecting their microbial fingerprint.
- Terroir Influence on Polyphenol Metabolism from Grape Canes: A Spatial Metabolomic Study at Parcel Scale10 juin 2023 - 10 juin 2025The aim of this study was to assess the terroir influence on the polyphenol composition ingrape canes using a spatial metabolomics approach.
Read more articles from 2023, 2022 and 2021
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